Rare peptide segments are found significantly more often in proto-oncoproteins than control proteins: implications for immunology and oncology
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چکیده
منابع مشابه
Rare peptide segments are found significantly more often in proto-oncoproteins than control proteins: implications for immunology and oncology.
There is some evidence to suggest that peptide segments that are found rarely or never in the host proteome play a role in the immune response to disease-related proteins, both those derived from microbes and those derived from the host itself. We conjecture that this pattern may extend to human proto-oncoproteins. Our hypothesis in this study is that the frequency of rare peptide segments in s...
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ژورنال
عنوان ژورنال: Journal of The Royal Society Interface
سال: 2008
ISSN: 1742-5689,1742-5662
DOI: 10.1098/rsif.2008.0320